Its seed has conventionally been used in india for the management of different diseases. The present investigation was aimed to determine the tocolytic activity of the aqueous seed extract of syzygium cumini. Collected seeds were washed in distilled water for about 15. Jamun benefits, usage, dose, side effects complete. Syzygium cumini has shown many pharmacologic properties including anti inflammatory. Aqueous extraction kinetics of phenolic compounds from jamun. Noted as naturalized in southern florida by 1982 wunderlin. Dec 14, 2012 phytochemical activity of seeds of syzygium cumini were performed to lay down the standards which could be useful in future experimental studies.
It is reported that seed extracts of syzygium cumini given to the animals with the dose of 5gmkg of bodyweight was more effective than the oral hypoglycaemic or. Supplementation of syzygium cumini seed powder prevented obesity, glucose intolerance, hyperlipidemia and oxidative stress in high carbohydrate high fat diet. Antibacterial and anticancer activity of bioactive. Pdf the therapeutic potential of syzygium cumini seeds in. Antimicrobial action of methanolic seed extracts of. Department of agriculture, with seeds from the philippines in 1911 and 1920, and from java and zanzibar in 1912 popenoe 1939.
Proximate composition of jamun syzygium cumini fruit and seed. The plant contains anthocyanins, glucoside, ellagic acid, isoquercetin, kaempferol, and myricetin as its chief active constituents. Ali 3 1department of pharmacognosy, kiet school of pharmacy, ghaziabad, up, india 2department of pharmacognosy. Whereas the crude extract exhibited, respectively, 33. Neutral components in the leaves and seeds of syzygium cumini. Although this species is well known by indonesian, the information about character of growth this species still limited. The major components of the leaves and seeds have the. Proximate composition of jamun syzygium cumini fruit and seed 11ahmad raza, muhammad usman ali, tanzeela nisar, 1 2 34saeed ahmad qasrani, riaz hussain and muhammad nawaz sharif 1national institute of food science and technology, university of agriculture faisalabad, pakistan. Syzygium cumini is used for the cure of various diseases including cough, diabetes, dysentery, inflammation and ringworm 7.
Supplementation of syzygium cumini seed powder prevented obesity, glucose intolerance, hyperlipidemia and oxidative. Antibacterial and anticancer activity of bioactive fraction. Exploration of preliminary phytochemical studies of seed of. It gives a new therapeutic paradigm as antihyperglycemic agent either due to a single component or combination of different.
Effects of ethanolic extract of syzygium cumini linn seed. Introduction jamun seed oil is a yellowish brown semi viscous liquid derived from the seeds of the plant syzygium cumini from family myrtaceae, commonly known as jambul, black plum, indian blackberry, jamblang or black cumin. Antiinflammatory action of seed extract and polymeric. It was noticed that the leaves also possess many other characteristic feature out of which the cure of diabetes is n of the important feature. Like tolbutamide the drug may also be promoting endogenous release of insulin. Both extracts exerted a broad spectrum of bacteriostatic action against different grampositive and.
Antibacterial and anticancer activity of bioactive fraction of. The name of the fruit is sometimes mistranslated as blackberry, which is a different fruit in an unrelated order. Here, we analyzed the antioxidant activity of leaves. The ripe berries are sweetish dry to taste and are useful in preparation of health drinks, jellies, juices squashes and wine. Seeds of syzygium cumini plant is of atmost importance. Leaves and seeds of syzygium cumini extracts produce significant. There are chemical compounds which occur naturally in plants and possess wide. Alloxan diabetes, ethanolic extract, pancreatic islets, s. Now one of the more rapidly spreading nonnative species, form. Jamun fruit seeds and pulp have been reported to serve various. Proximate composition of jamun syzygium cumini fruit. Biosynthesis of silver nanoparticles from syzygium cumini l.
Aqueous extraction kinetics of phenolic compounds from. Viability and vigor of jamun syzygium cumini seeds scielo. The fruits, leaves, barks and seeds of this unique plant can be used for a myriad of health conditions. Antibacterial study and effect of ethanolic extracts of syzygium. Aug 08, 1985 syzygium cumini seed kernel aqueous suspension was screened for its antibiadetic activity at the dose levels of 1g.
This study shows that extract of syzygium cumini fruit skin along with the outermost layer of the berry inhibits growth and induces apoptosis in both hela and siha cervical cancer cell lines in a dose and timedependent manner. Recent advances in pharmacological potential of syzygium cumini. An excellent, if rather terse, guide to the traditional medicinal uses of the plants of the region the reddishgrey or reddishbrown heartwood is fine grained and is utilized in exterior joinery and carpentry. Syzygium cumini seeds, java plum, malabar plum, portuguese plum, fruit seeds from thailand syzygium cumini, known as jambul, jambolan, jamblang or jamun, is an evergreen tropical tree in the flowering plant family myrtaceae. Syzygium cumini, commonly known as malabar plum, java plum, or black plum, is an evergreen tropical tree in the flowering plant family myrtaceae. Abstract viability and vigor of jamun syzygium cumini seeds. Issn 23203862 the therapeutic potential of syzygium. Studies have indicated that ethyl acetic and methanolic extracts from s. Ali 3 1department of pharmacognosy, kiet school of pharmacy, ghaziabad, up, india 2department of pharmacognosy, bbs institute of pharmacy, greater noida, up, india.
It is native to the indian subcontinent, adjoining regions of southeast asia, china and queensland. A traditional therapeutic tree and its processed food products. Previous report also suggests that syzygium cumini fruit extract possesses hypoglycemic action in diabetic rats 12. Evaluation of antioxidant activity in different parts of syzygium cumini linn. Older reports from indian medical journals suggest jambul seed and bark can be beneficial in humans with diabetes 25. The extract showed to possess high amount of polyphenols, significant in vitro free radical scavenger activity using the dpph method and an. The results revealed the presence of medicinally important phytochemical constituents in the ethyl acetate and methanol extracts of syzygium cumini seeds and it justifies their use in the traditional medicines for the treatment of different diseases.
The next time you eat jamuns, do not throw away its seeds. During the last 125 year research which was much before the discovery of insulin many evidence were seen which defined that seeds of these plants. Fractionation of antibacterial extracts of syzygium cumini. Pdf antibacterial and anticancer activity of bioactive. Different parts of jamun have been used to cure blisters in the mouth, colic, di. Phytochemical composition and pleotropic pharmacological. The collected jamun seed were washed and sun dried for 78 days to dry them. Syzygium cumini inhibits growth and induces apoptosis in. Buy foodherbs jamun seed syzygium cumini seed powder 200 gm0. Jamun characteristics jamun, syzygium cumini belongs to family. The effects of various parameters such as extraction temperature 34.
The website also provides access to a database and images of herbarium specimens found at the university of south florida and other herbaria. Leaves and seeds of syzygium cumini extracts produce. Syzygium cumini, generally recognized as jamun, is a tropical tree that produces purple ovoid fleshy fruit. Syzygium jambolana, eugenia jambolana, eugenia cumini belong to polyembryonic species of the family myrtaceae, commonly known as indian blackberry or jamun. Skeels black plum, damson plum fruits weigh between 25 g at maturity. Biosynthesis of silver nanoparticles from syzygium cumini. Syzygium cumini is widely used in traditional medicine to treat diabetes in india. Recent advances in pharmacological potential of syzygium. A downloadable pdf document of a book in prepublication awaiting illustration. Singh and gupta 2007, investigated the effects of ethanolic extract of syzygium cumini l.
The role of syzygium cumini against chronic complications of diabetes mellitus dm, such as fungal infection and inflammation, has been poorly explored. Syzygium cumini and its seed a member of myrtaceae family acquire potential role in regulating diabetes mellitus and its seeds are moderately. The syzygium cumini has medicinal importance as an antiinflammatory, antibacterial, antiulcergenic. Among other things, it is especially beneficial in controlling blood sugar levels in diabetics. Introduction a long term endocrine metabolic disorder characterized by hyperglycemia is commonly known as diabetes. Linn seed powder on pancreatic islets of alloxan diabetic rats. Syzygium cumini seed kernel aqueous suspension was screened for its antibiadetic activity at the dose levels of 1g. Skeels, myrtaceae, obtained by dynamic maceration was spraydried and characterized by its physicochemical and antihyperglycaemic action. Skeels myrtaceae, is a tree popularly known as jambolan in brazil, jamun in india, black plum in europe, among others, whose antidiabetic effects have been widely studied, especially due to its low toxicity 15. Abstractin this study, aqueous extraction of phenolic compounds from jamun syzygium cumini l.
Syzygium cumini is a well known bioactive plant which has been widely used for the treatment of various diseases in traditional and folk medicine. Entire plant of syzygium cumini such as seed, fruit, leaves, flower, bark used in folk medicine. Antidiabetic activity and phytochemical constituents of. Antimicrobial action of methanolic seed extracts of syzygium. Syzygium cumini linn family myrtaceae1 commonly known as.
Myrtaceae jambolan, java plum, jamun, naval, neredu, indian allspice. Charaka used seeds, leaves and fruits in decoctions for diarrhoea. Plants have been employed as medicine since time immemorial, and there has been a recent resurgence in the use of plants as medicines due to their little or no toxicity at the doses used for treatment of different ailments. Skeels jambolan is one of the widely used medicinal plants in the treatment of various diseases in particular diabetes. Effects of ethanolic extract of syzygium cumini linn.
Keywords syzygium cumini, jamun seed oil, solvent extraction, physicochemical properties, saponification value. Syzygium cumini is an evergreen tree habitat in bangladesh, india, eastern africa, south america and madagascar. International journal of current microbiology and applied sciences, 2015, 4 9, 372379. Syzygium cumini seed extracts prepared in methanol and ethanol was. Various parts of plant including seeds, bark, leaves and fruits had been studied and investigated for various pharmacological properties. One of the best medicinal benefits of syzygium cumini is its antidiabetic properties exhibited by the phytochemicals in its fruits and leaves. Amylase inhibitors from syzygium cumini linn seeds 679 dragendorffs reagent, identified the presence of phenolics, terpenoids and alkaloids, respectively in the extract. Hyperlipidemia was induced in rats by giving high cholesterol diet 2% cholesterol, 1% sodium cholate and 2% coconut oil for seven days in standard rat chow diet.
Antibacterial activity of syzygium cumini seed extracts prepared in methanol and ethanol was evaluated by disc diffusion and broth dilution assays. Seeds of syzygium cumini l, family myrtaceae commonly known as jamun in hindi, black plum in english, neredam in tamil and neereedu in telegu posses hypoglycaemic properties18. India was previously called as jambudveepa an island where jambu trees are abundant. Another aspect of the study was to evaluate the anti microbial activity of the different parts of the plant, keeping in view its pharmacological potential. Syzygium cumini is a medicinal plant whose seeds have been pharmacologically proved to possess hypoglycemic, antibacterial, antiinflammatory, antihuman immunodeficiency virus hiv, and antidiarrheal effects sharma et al. Syzygium cumini, antidiabetic, diabetes mellitus, pharmacological attributes, folk medicines 1. The present study was carried out to evaluate the phytochemical bioactive compounds from syzygium cumini seed extract and its invitro antidiabetic activity. Evaluation of antioxidant activity in different parts of. Pdf viability and vigor of jamun syzygium cumini seeds. Syzygium cumini extract showed antiinflammatory activity in animal model 9, 10. Syzygium cumini, syzygium jambolanum, eugenia cumini, eugenia. The bark, the fruit, the seeds as well as the leaves are.
The inhibition obtained in other medicinal plants ranged from 0 to 20% table 1. Syzygium cumini jamun seeds have hypoglycaemic5,6,7, antiinflammatory8, antipyretic9. The collected fruits were divided into three lots for experimental purposes. Potential glucosidase and amylase inhibition ic 50 1.
The therapeutic potential of syzygium cumini seeds in diabetes mellitus kumari binita, veena sharma and savita yadav abstract diabetes mellitus dm type ii is a long term endocrine metabolic disorder due to disturbances in metabolism of carbohydrate, fat, protein and characterized by hyperglycemia. The sweet fruit is readily consumed by a variety of animals which, along with water, spread seeds widely. The study includes macroscopy, microscopy, preliminary phytochemical screening and physicochemical evaluation of seeds of syzygium cumini. Traditionally the syzygium cumini fruits, leaves, seeds, and bark are used in ayurvedic medicine 7. Jamun benefits, usage, dose, side effects complete ayurveda. Syzygium cumini journal of chemical and pharmaceutical research.
Long recommended as a shade tree but considered messy broschat and meerow 1991. Exploration of preliminary phytochemical studies of seed. Syzygium cumini has shown many pharmacologic properties including antiinflammatory. The present study evaluated antidiabetic potential of fractions of syzygium cumini seeds and identified major polyphenolic compounds in them. In this present study, we mainly focused on the effect of syzygium cumini to control diabetes mellitus. Syzygium cumini extract also reduced the production of prostaglandin e 2, serotonin, and histamine in vivo 11. It is known as duwet, juwet, jamblang, etc in indonesia. Kamal a, phytochemical screening of syzygium cumini seeds, indian journal of plant sciences, 2014, 3 4. Fresh seeds represented 2080% of the total fruit weight. Uses, side effects, interactions, dosage, and warning. Phytochemical screening of syzygium cumini myrtaceae. Jun 07, 2017 4 health benefits of jamun seeds you need to know about.
The jambosin phytochemical plays an important role in converting sugar in the body into energy. Pharmacological activities of jamun, syzygium cumini j explor res pharmacol java plum, malabar plum, duhat and portuguese plum. The seeds of syzygium cumini possess antidiabetic, antipyretic, hypolipidaemic, psychopharmacological, antidiarrheal, antiinflammatory, antioxidant and antibacterial activities. Myrtaceae and is also known as eugenia cumini druce. Syzygium cumini and its seed a member of myrtaceae family acquire potential role in regulating diabetes mellitus and its seeds are moderately rich in protein 6. Issn 23203862 the therapeutic potential of syzygium cumini. The phytochemical screening showed appreciable amount of flavonoid and steroid in the seed extract. Syzygium cumini, syzygium jambolanum, eugenia cumini, eugenia jambolana family. And, dry powder of jamun seeds biochemically analyzed for moisture 70. Extraction and characterization of syzygium cumini jamun. Antibacterial and anticancer activity of bioactive fraction of syzygium cumini l. Here, we analyzed the antioxidant activity of leaves and seeds from aqueous extracts of s.
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